Platinum and platinum compounds; Health-based recommended occupational exposure limit

At the request of the Minister of Social Affairs and Employment, the Health Council of the Netherlands recommends health-based occupational exposure limits for the concentration of toxic substances in the air at the workplace. These recommendations are made by the Council’s Dutch Expert Committee on Occupational Standards (DECOS).
The present advice on platinum and platinum compounds was prepared in cooperation with the Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals (NEG), an advisory body of the Nordic countries. The joint report on the consequences of occupational exposure to platinum and platinum compounds, published in Sweden in 1997 (Arbete och Hälsa 1997:14) is included in Part II of this document. Part I consists of a summary of the data presented in Part II, presentation of data becoming available since 1997, and a discussion of the consequences of occupational exposure to platinum and its compounds. The conclusions in this advice are based on scientific publications which appeared before September 2007, and are entirely DECOS’ view.

Committee

• G.J. Mulder, emeritus professor of toxicology; Leiden University, Leiden, chairman
• R.B. Beems, toxicologic pathologist; National Institute for Public Health and the Environment, Bilthoven
• P.J. Boogaard, toxicologist; Shell International BV, The Hague
• J.J.A.M. Brokamp, Social and Economic Council, The Hague, advisor
• D.J.J. Heederik, professor of risk assessment in occupational epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht
• L.A.L.M. Kiemeney, professor of cancer epidemiology, University Medical Centre St Radboud, Nijmegen
• H. van Loveren, professor of immunotoxocology; Maastricht University, Maastricht, and National Institute for Public Health and the Environment, Bilthoven
• T.M. Pal, occupational physician, Netherlands Center for Occupational Diseases, Amsterdam
• A.H. Piersma, professor of reproductive toxicology, National Institute for Public Health and the Environment, Bilthoven
• H.P.J. te Riele, professor of molecular biology, VU University Amsterdam, Amsterdam
• I.M.C.M. Rietjens, professor of toxicology, Wageningen University and Research Centre, Wageningen
• H. Roelfzema, Ministry of Health, Welfare and Sport, The Hague, advisor
• T. Smid, occupational hygienist - epidemiologist; KLM Health Services, Schiphol, and professor of working conditions, VU University Amsterdam, Amsterdam
• G.M.H. Swaen, epidemiologist; Dow Benelux N.V., Terneuzen
• R.A. Woutersen, toxicologic pathologist, TNO Quality of Life, Zeist
• P.B. Wulp, occupational physician; Labour Inspectorate, Groningen
• J.T.J. Stouten, Health Council of the Netherlands, The Hague, scientific secretary