Acrylamide; Health-based calculated occupational cancer risk values

At the request of the Minister of Social Affairs and Employment, the Dutch Expert Committee on Occupational Standards (DECOS), a committee of the Health Council of the Netherlands, derives so-called health-based calculated – occupational cancer risk values (HBC-OCRVs) associated with excess mortality levels of 4 per 1,000 and 4 per 100,000 as a result of working life exposure to substances, that have been classified by the European Union or the DECOS as genotoxic carcinogen. In this report the committee presents such estimates for acrylamide. For the estimation, the committee used the method described in the report ‘Calculating cancer risk due to occupational exposure to genotoxic carcinogens’.

Committee

• GJ Mulder, chairman
  emeritus professor of toxicology, Leiden
• RB Beems
  toxicologic pathologist; National Institute of Public Health and the Environment, Bilthoven
• LJNGM Bloemen
  epidemiologist; Exponent Inc., Terneuzen
• PJ Boogaard
  toxicologist; SHELL International BV, The Hague
• PJ Borm
  toxicologist; Centre of Expertise in Life Sciences, Hogeschool Zuyd, Heerlen
• JJAM Brokamp, advisor
  Social and Economic Council, The Hague
• DJJ Heederik
  professor of risk assessment in occupational epidemiology; IRAS, University of Utrecht, Utrecht
• TM Pal
  occupational physician; Dutch Centre for Occupational Diseases, Amsterdam
• IM Rietjens
  professor of toxicology; Wageningen University, Wageningen.
• T Smid
  occupational hygienist/epidemiologist; KLM Health Safety & Environment, Schiphol; and, professor of working conditions, Free University, Amsterdam
• GMH Swaen
  epidemiologist; Dow Chemical Company, the Netherlands
• RA Woutersen
  toxicologic pathologist; TNO Quality of Life, Zeist
• P Wulp
  occupational physician; Labour Inspectorate, Groningen
• ASAM van der Burght, scientific secretary
  Health Council of the Netherlands, The Hague
• JM Rijnkels, scientific secretary
  Health Council of the Netherlands, The Hague